2XA7
AP2 clathrin adaptor core in active complex with cargo peptides
Summary for 2XA7
Entry DOI | 10.2210/pdb2xa7/pdb |
Related | 1BW8 1BXX 1E42 1HES 1I31 2BP5 2G30 2IV8 2IV9 2JKR 2JKT 2VGL 2XA8 |
Descriptor | ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU,, ... (6 entities in total) |
Functional Keywords | phosphoprotein, protein transport, endocytosis, cell membrane, lipid-binding |
Biological source | RATTUS NORVEGICUS (RAT) More |
Cellular location | Cell membrane: P63010 P62743 Cell membrane (By similarity): P84092 |
Total number of polymer chains | 5 |
Total formula weight | 206119.62 |
Authors | Jackson, L.P.,Kelly, B.T.,McCoy, A.J.,Evans, P.R.,Owen, D.J. (deposition date: 2010-03-29, release date: 2010-07-21, Last modification date: 2024-05-08) |
Primary citation | Jackson, L.P.,Kelly, B.T.,Mccoy, A.J.,Gaffry, T.,James, L.C.,Collins, B.M.,Honing, S.,Evans, P.R.,Owen, D.J. A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex Cell(Cambridge,Mass.), 141:1241-, 2010 Cited by PubMed: 20603002DOI: 10.1016/J.CELL.2010.05.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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