2X99

Thioredoxin glutathione reductase from Schistosoma mansoni in complex with NADPH

Summary for 2X99

Entry DOI	10.2210/pdb2x99/pdb
Related	2V6O 2X8C 2X8G 2X8H
Descriptor	THIOREDOXIN GLUTATHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (8 entities in total)
Functional Keywords	flavoprotein, oxidoreductase, thioredoxin, glutathione, nadph, detoxification pathway
Biological source	SCHISTOSOMA MANSONI
Total number of polymer chains	1
Total formula weight	68854.69
Authors	Angelucci, F.,Dimastrogiovanni, D.,Boumis, G.,Brunori, M.,Miele, A.E.,Saccoccia, F.,Bellelli, A. (deposition date: 2010-03-15, release date: 2010-07-21, Last modification date: 2017-07-12)
Primary citation	Angelucci, F.,Dimastrogiovanni, D.,Boumis, G.,Brunori, M.,Miele, A.E.,Saccoccia, F.,Bellelli, A. Mapping the Catalytic Cycle of Schistosoma Mansoni Thioredoxin Glutathione Reductase by X-Ray Crystallography J.Biol.Chem., 285:32557-, 2010 Cited by PubMed: 20659890 DOI: 10.1074/JBC.M110.141960 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation