2X7G

Structure of human serine-arginine-rich protein-specific kinase 2 (SRPK2) bound to purvalanol B

Summary for 2X7G

• Entry DOI: 10.2210/pdb2x7g/pdb
• Descriptor: UNCHARACTERIZED PROTEIN SRPK2, PURVALANOL B, SULFATE ION, ... (6 entities in total)
• Functional Keywords: serine/threonine-protein kinase, mrna splicing, phosphoprotein, mrna processing, differentiation, nucleotide-binding, spliceasome assembly, atp competitive inhibitor, kinase, nucleus, transferase, atp-binding, splice factor trafficking
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 45837.47

Authors

Pike, A.C.W.,Savitsky, P.,Fedorov, O.,Krojer, T.,Ugochukwu, E.,von Delft, F.,Gileadi, O.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Knapp, S. (deposition date: 2010-02-26, release date: 2010-04-14, Last modification date: 2023-12-20)

• Primary citation: Pike, A.C.W.,Savitsky, P.,Fedorov, O.,Krojer, T.,Ugochukwu, E.,von Delft, F.,Gileadi, O.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Knapp, S.; Structure of Human Serine-Arginine-Rich Protein- Specific Kinase 2 (Srpk2) Bound to Purvalanol B; To be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)