2X7G

Structure of human serine-arginine-rich protein-specific kinase 2 (SRPK2) bound to purvalanol B

2X7G の概要

分子名称UNCHARACTERIZED PROTEIN SRPK2, PURVALANOL B, SULFATE ION, ... (6 entities in total)
機能のキーワードserine/threonine-protein kinase, mrna splicing, phosphoprotein, mrna processing, differentiation, nucleotide-binding, spliceasome assembly, atp competitive inhibitor, kinase, nucleus, transferase, atp-binding, splice factor trafficking
由来する生物種HOMO SAPIENS (HUMAN)
ポリマー鎖数1
分子量合計45837.47
構造登録者
主引用文献
Pike, A.C.W.,Savitsky, P.,Fedorov, O.,Krojer, T.,Ugochukwu, E.,von Delft, F.,Gileadi, O.,Edwards, A.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Knapp, S.
Structure of Human Serine-Arginine-Rich Protein- Specific Kinase 2 (Srpk2) Bound to Purvalanol B
To be Published,
実験手法
X-RAY DIFFRACTION (2.5 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23920.3%1.7%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード