Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2X7F

Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor

Summary for 2X7F
Entry DOI10.2210/pdb2x7f/pdb
DescriptorTRAF2 AND NCK-INTERACTING PROTEIN KINASE, 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, SODIUM ION, ... (4 entities in total)
Functional Keywordsserine/threonine-protein kinase, phosphoprotein, kinase, transferase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus: Q9UKE5
Total number of polymer chains5
Total formula weight187959.49
Authors
Primary citationVollmar, M.,Alfano, I.,Shrestha, B.,Bray, J.,Muniz, J.R.C.,Roos, A.,Filippakopoulos, P.,Burgess-Brown, N.,Ugochukwu, E.,Gileadi, O.,Phillips, C.,Mahajan, P.,Pike, A.C.W.,Fedorov, O.,Chaikuad, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S.
Crystal Structure of the Kinase Domain of Human Traf2- and Nck-Interacting Kinase with Wee1Chk1 Inhibitor
To be Published,
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon