2X7F
Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | TRAF2 AND NCK-INTERACTING PROTEIN KINASE | polymer | 326 | 37240.6 | 5 | UniProt (Q9UKE5) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | |
| 2 | A, B, C, D, E | 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE | non-polymer | 328.3 | 5 | Chemie (824) | |||
| 3 | A, B, C, D, E | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 4 | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 325 (UniProt: Q9UKE5)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 186202.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1756.6 | |
| All* | Total formula weight | 187959.5 |
