2X5W
X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with substrate cholest-4-en-3-one
Summary for 2X5W
Entry DOI | 10.2210/pdb2x5w/pdb |
Related | 2X5L |
Descriptor | PUTATIVE CYTOCHROME P450 125, SULFATE ION, (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ... (6 entities in total) |
Functional Keywords | cholesterol degradation, metal-binding, oxidoreductase |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 1 |
Total formula weight | 50610.82 |
Authors | Ouellet, H.,Guan, S.,Johnston, J.B.,Chow, E.D.,Kells, P.M.,Burlingame, A.L.,Cox, J.S.,Podust, L.M.,Ortiz de Montellano, P.R. (deposition date: 2010-02-10, release date: 2010-06-16, Last modification date: 2023-12-20) |
Primary citation | Ouellet, H.,Guan, S.,Johnston, J.B.,Chow, E.D.,Kells, P.M.,Burlingame, A.L.,Cox, J.S.,Podust, L.M.,Ortiz de Montellano, P.R. Mycobacterium Tuberculosis Cyp125A1, a Steroid C27 Monooxygenase that Detoxifies Intracellularly Generated Cholest-4-En-3-One. Mol.Microbiol., 77:730-, 2010 Cited by PubMed: 20545858DOI: 10.1111/J.1365-2958.2010.07243.X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.58 Å) |
Structure validation
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