2X30

Crystal structure of the r139n mutant of a bifunctional enzyme pria

Summary for 2X30

• Entry DOI: 10.2210/pdb2x30/pdb
• Related: 1VZW 2VEP
• Descriptor: PHOSPHORIBOSYL ISOMERASE A, SULFATE ION (3 entities in total)
• Functional Keywords: aromatic amino acid biosynthesis, tryptophan biosynthesis, conformational diversity, dual-substrate specificity, histidine biosynthesis, isomerase, loops motion, hisa, trpf
• Biological source: STREPTOMYCES COELICOLOR
• Cellular location: Cytoplasm : P16250
• Total number of polymer chains: 1
• Total formula weight: 25255.28

Authors

Noda-Garcia, L.,Camacho-Zarco, A.R.,Verdel-Aranda, K.,Wright, H.,Soberon, X.,Fulop, V.,Barona-Gomez, F. (deposition date: 2010-01-20, release date: 2010-02-02, Last modification date: 2023-12-20)

• Primary citation: Noda-Garcia, L.,Camacho-Zarco, A.R.,Verdel-Aranda, K.,Wright, H.,Soberon, X.,Fulop, V.,Barona-Gomez, F.; Identification and Analysis of Residues Contained on Beta --> Alpha Loops of the Dual-Substrate (Betaalpha)(8) Phosphoribosyl Isomerase a (Pria) Specific for its Phosphoribosyl Anthranilate Isomerase Activity.; Protein Sci., 19:535-, 2010; PubMed: 20066665; DOI: 10.1002/PRO.331

Experimental method

X-RAY DIFFRACTION (1.95 Å)