2X15

The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP and 1,3- bisphosphoglycerate

Summary for 2X15

• Entry DOI: 10.2210/pdb2x15/pdb
• Related: 2WZB 2WZC 2WZD 2X13 2X14 2XE6 2XE7 2XE8 2Y3I
• Descriptor: PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: transition state analogue, hereditary hemolytic anemia, phosphoprotein, kinase, glycolysis, transferase, phosphoryl transfer, nucleotide-binding
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: P00558
• Total number of polymer chains: 1
• Total formula weight: 45952.21

Authors

Bowler, M.W.,Cliff, M.J.,Marston, J.P.M.,Baxter, N.J.,Hounslow, A.M.H.,Varga, A.V.,Szabo, J.,Vas, M.,Blackburn, G.M.,Waltho, J.P. (deposition date: 2009-12-21, release date: 2011-02-09, Last modification date: 2023-12-20)

• Primary citation: Bowler, M.W.,Cliff, M.J.,Marston, J.P.M.,Baxter, N.J.,Hounslow, A.M.H.,Varga, A.V.,Szabo, J.,Vas, M.,Blackburn, G.M.,Waltho, J.P.; The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analoges; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)