2X11

Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain

2X11 の概要

• エントリーDOI: 10.2210/pdb2x11/pdb
• 関連するPDBエントリー: 1MQB 2X10
• 分子名称: EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5 (2 entities in total)
• 機能のキーワード: receptor-signaling protein complex, developmental protein, signaling platform, kinase, transferase, neurogenesis, receptor, cataract, apoptosis, erythropoietin-producing hepatocellular carcinoma, angiogenesis, signaling protein, receptor/signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80261.54

構造登録者

Seiradake, E.,Harlos, K.,Sutton, G.,Aricescu, A.R.,Jones, E.Y. (登録日: 2009-12-21, 公開日: 2010-03-16, 最終更新日: 2023-12-20)

• 主引用文献: Seiradake, E.,Harlos, K.,Sutton, G.,Aricescu, A.R.,Jones, E.Y.; An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly; Nat.Struct.Mol.Biol., 17:398-, 2010; PubMed: 20228801; DOI: 10.1038/NSMB.1782

実験手法

X-RAY DIFFRACTION (4.83 Å)