2WZM

Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form

Summary for 2WZM

• Entry DOI: 10.2210/pdb2wzm/pdb
• Related: 2WZT
• Descriptor: ALDO-KETO REDUCTASE, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE (3 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: MYCOBACTERIUM SMEGMATIS
• Total number of polymer chains: 2
• Total formula weight: 61193.21

Authors

Scoble, J.,McAlister, A.D.,Fulton, Z.,Troy, S.,Byres, E.,Vivian, J.P.,Brammananth, R.,Wilce, M.C.J.,Le Nours, J.,Zaker-Tabrizi, L.,Coppel, R.L.,Crellin, P.K.,Rossjohn, J.,Beddoe, T. (deposition date: 2009-11-30, release date: 2010-02-16, Last modification date: 2024-05-08)

• Primary citation: Scoble, J.,Mcalister, A.D.,Fulton, Z.,Troy, S.,Byres, E.,Vivian, J.P.,Brammananth, R.,Wilce, M.C.J.,Le Nours, J.,Zaker-Tabrizi, L.,Coppel, R.L.,Crellin, P.K.,Rossjohn, J.,Beddoe, T.; Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase.; J.Mol.Biol., 398:26-, 2010; PubMed: 20188740; DOI: 10.1016/J.JMB.2010.02.021

Experimental method

X-RAY DIFFRACTION (1.64 Å)