2WWE

Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma

Summary for 2WWE

• Entry DOI: 10.2210/pdb2wwe/pdb
• Descriptor: PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE (2 entities in total)
• Functional Keywords: phosphoprotein, nucleotide-binding, kinase, pik3c2g, membrane, px-domain, transferase, atp-binding, polymorphism, class 2 pi3k
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 14977.65

Authors

Roos, A.K.,Tresaugues, L.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotyenova, T.,Kotzch, A.,Kraulis, P.,Markova, N.,Moche, M.,Nielsen, T.K.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Van Der Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Wisniewska, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2009-10-22, release date: 2009-11-03, Last modification date: 2023-12-20)

• Primary citation: Roos, A.K.,Tresaugues, L.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotyenova, T.,Kotzch, A.,Kraulis, P.,Markova, N.,Moche, M.,Nielsen, T.K.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Wisniewska, M.,Nordlund, P.,Structural Genomics Consortium (SGC); Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma; To be Published,

Experimental method

X-RAY DIFFRACTION (1.25 Å)