2WUL
CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER
Replaces: 2WEMSummary for 2WUL
Entry DOI | 10.2210/pdb2wul/pdb |
Descriptor | GLUTAREDOXIN RELATED PROTEIN 5, GLUTATHIONE, FE2/S2 (INORGANIC) CLUSTER, ... (6 entities in total) |
Functional Keywords | chromosome 14 open reading frame 87, oxidoreductase, thioredoxin family, glrx5, pr01238, flb4739 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion matrix : Q86SX6 |
Total number of polymer chains | 4 |
Total formula weight | 53291.12 |
Authors | Roos, A.K.,Johansson, C.,Guo, K.,Yue, W.W.,Pike, A.C.W.,Cooper, C.D.O.,Pilka, E.S.,Kavanagh, K.L.,Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2009-10-06, release date: 2009-10-20, Last modification date: 2023-12-20) |
Primary citation | Johansson, C.,Roos, A.K.,Montano, S.J.,Sengupta, R.,Filippakopoulos, P.,Guo, K.,von Delft, F.,Holmgren, A.,Oppermann, U.,Kavanagh, K.L. The Crystal Structure of Human Glrx5: Iron Sulphur Cluster Coordination, Tetrameric Assembly and Monomer Activity. Biochem.J., 433:303-, 2011 Cited by PubMed: 21029046DOI: 10.1042/BJ20101286 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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