2WTX

Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase

2WTX の概要

• エントリーDOI: 10.2210/pdb2wtx/pdb
• 関連するPDBエントリー: 1GZ5 1UQT 1UQU
• 分子名称: ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING], 1,2-ETHANEDIOL, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: trehalose synthase, glycosyltransferase, potassium, retention, transferase, stress response
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 218292.20

構造登録者

Errey, J.C.,Lee, S.S.,Gibson, R.P.,Martinez-Fleites, C.,Barry, C.S.,Jung, P.M.J.,OSullivan, A.,Davis, B.G.,Davies, G.J. (登録日: 2009-09-25, 公開日: 2010-02-23, 最終更新日: 2023-12-20)

• 主引用文献: Errey, J.C.,Lee, S.S.,Gibson, R.P.,Martinez Fleites, C.,Barry, C.S.,Jung, P.M.J.,O'Sullivan, A.C.,Davis, B.G.,Davies, G.J.; Mechanistic Insight Into Enzymatic Glycosyl Transfer with Retention of Configuration Through Analysis of Glycomimetic Inhibitors.; Angew.Chem.Int.Ed.Engl., 49:1234-, 2010; PubMed: 20077550; DOI: 10.1002/ANIE.200905096

実験手法

X-RAY DIFFRACTION (2.2 Å)