2WT7

Crystal structure of the bZIP heterodimeric complex MafB:cFos bound to DNA

2WT7 の概要

• エントリーDOI: 10.2210/pdb2wt7/pdb
• 分子名称: PROTO-ONCOGENE PROTEIN C-FOS, TRANSCRIPTION FACTOR MAFB, MODIFIED T-MARE MOTIF, ... (6 entities in total)
• 機能のキーワード: transcription, transcription regulation, nucleus, activator, repressor, dna-binding, phosphoprotein, differentiation, tumor suppressor, proliferation, proto-oncogene
• 由来する生物種: MUS MUSCULUS (HOUSE MOUSE); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28329.59

構造登録者

Pogenberg, V.,Holton, S.,Wilmanns, M. (登録日: 2009-09-11, 公開日: 2010-09-29, 最終更新日: 2019-07-17)

• 主引用文献: Pogenberg, V.,Consani Textor, L.,Vanhille, L.,Holton, S.J.,Sieweke, M.H.,Wilmanns, M.; Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.; Structure, 22:466-, 2014; PubMed: 24530283; DOI: 10.1016/J.STR.2013.12.017

実験手法

X-RAY DIFFRACTION (2.3 Å)