2WME

Crystallographic structure of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa

Replaces:  2VE5

Summary for 2WME

• Entry DOI: 10.2210/pdb2wme/pdb
• Descriptor: BETAINE ALDEHYDE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, BETA-MERCAPTOETHANOL, ... (7 entities in total)
• Functional Keywords: aldehyde oxidation, nad, nadp complex, oxidoreductase
• Biological source: PSEUDOMONAS AERUGINOSA; More
• Total number of polymer chains: 8
• Total formula weight: 436051.54

Authors

Gonzalez-Segura, L.,Rudino-Pinera, E.,Munoz-Clares, R.A.,Horjales, E. (deposition date: 2009-06-30, release date: 2009-08-04, Last modification date: 2023-12-13)

• Primary citation: Gonzalez-Segura, L.,Rudino-Pinera, E.,Munoz-Clares, R.A.,Horjales, E.; The Crystal Structure of a Ternary Complex of Betaine Aldehyde Dehydrogenase from Pseudomonas Aeruginosa Provides New Insight Into the Reaction Mechanism and Shows a Novel Binding Mode of the 2'- Phosphate of Nadp(+) and a Novel Cation Binding Site.; J.Mol.Biol., 385:542-, 2009; PubMed: 19013472; DOI: 10.1016/J.JMB.2008.10.082

Experimental method

X-RAY DIFFRACTION (2.1 Å)