2WM4

X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP124 in complex with phytanic acid

2WM4 の概要

• エントリーDOI: 10.2210/pdb2wm4/pdb
• 関連するPDBエントリー: 2WM5
• 分子名称: PUTATIVE CYTOCHROME P450 124, PROTOPORPHYRIN IX CONTAINING FE, (3R,7S,11S)-3,7,11,15-tetramethylhexadecanoic acid, ... (5 entities in total)
• 機能のキーワード: metal-binding, oxidoreductase, omega-hydroxylation, p450, iron, heme, fatty acid, monooxygenase
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 49808.03

構造登録者

Johnston, J.B.,Kells, P.M.,Podust, L.M.,Ortiz de Montellano, P.R. (登録日: 2009-06-30, 公開日: 2009-10-06, 最終更新日: 2023-12-13)

• 主引用文献: Johnston, J.B.,Kells, P.M.,Podust, L.M.,Ortiz de Montellano, P.R.; Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis.; Proc. Natl. Acad. Sci. U.S.A., 106:20687-20692, 2009; PubMed: 19933331; DOI: 10.1073/pnas.0907398106

実験手法

X-RAY DIFFRACTION (2.11 Å)