2WJY
Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form
Summary for 2WJY
Entry DOI | 10.2210/pdb2wjy/pdb |
Related | 2IYK 2WJV |
Descriptor | REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nonsense mediated decay, zinc-finger, atp-binding, metal-binding, upf2, upf1, helicase, hydrolase, nonsense-mediated mrna decay, phosphoprotein, nucleotide-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q92900 |
Total number of polymer chains | 1 |
Total formula weight | 90948.97 |
Authors | Clerici, M.,Mourao, A.,Gutsche, I.,Gehring, N.H.,Hentze, M.W.,Kulozik, A.,Kadlec, J.,Sattler, M.,Cusack, S. (deposition date: 2009-06-01, release date: 2009-07-07, Last modification date: 2023-12-13) |
Primary citation | Clerici, M.,Mourao, A.,Gutsche, I.,Gehring, N.H.,Hentze, M.W.,Kulozik, A.,Kadlec, J.,Sattler, M.,Cusack, S. Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28:2293-, 2009 Cited by PubMed: 19556969DOI: 10.1038/EMBOJ.2009.175 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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