2WJV
Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2
Summary for 2WJV
Entry DOI | 10.2210/pdb2wjv/pdb |
Related | 1UW4 2IYK 2WJY |
Descriptor | REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, ZINC ION, ... (4 entities in total) |
Functional Keywords | hydrolase, zinc-finger, atp-binding, rna-binding, nonsense-mediated mrna decay, nucleotide-binding, metal-binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm: Q92900 Cytoplasm, perinuclear region: Q9HAU5 |
Total number of polymer chains | 4 |
Total formula weight | 203850.90 |
Authors | Clerici, M.,Mourao, A.,Gutsche, I.,Gehring, N.H.,Hentze, M.W.,Kulozik, A.,Kadlec, J.,Sattler, M.,Cusack, S. (deposition date: 2009-06-01, release date: 2009-07-07, Last modification date: 2023-12-13) |
Primary citation | Clerici, M.,Mourao, A.,Gutsche, I.,Gehring, N.H.,Hentze, M.W.,Kulozik, A.,Kadlec, J.,Sattler, M.,Cusack, S. Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28:2293-, 2009 Cited by PubMed: 19556969DOI: 10.1038/EMBOJ.2009.175 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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