2WIO

Structure of the histidine tagged, open cytochrome P450 Eryk from S. erythraea

Summary for 2WIO

Entry DOI	10.2210/pdb2wio/pdb
Related	2JJN 2JJO 2JJP 2VRU 2VRV
Descriptor	ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	substrate specificity, antibiotic biosynthesis, metal-binding, oxidoreductase, cytochrome p450, iron, heme, erythromicyn, monooxygenase
Biological source	SACCHAROPOLYSPORA ERYTHRAEA
Total number of polymer chains	1
Total formula weight	48134.86
Authors	Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kedrew, S.G.,Gianni, S.,Vallone, B. (deposition date: 2009-05-14, release date: 2009-07-21, Last modification date: 2023-12-13)
Primary citation	Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Jemth, P.,Gianni, S.,Vallone, B. Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate. J.Biol.Chem., 284:29170-, 2009 Cited by PubMed: 19625248 DOI: 10.1074/JBC.M109.003590 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation