2WIO

Structure of the histidine tagged, open cytochrome P450 Eryk from S. erythraea

2WIO の概要

• エントリーDOI: 10.2210/pdb2wio/pdb
• 関連するPDBエントリー: 2JJN 2JJO 2JJP 2VRU 2VRV
• 分子名称: ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• 機能のキーワード: substrate specificity, antibiotic biosynthesis, metal-binding, oxidoreductase, cytochrome p450, iron, heme, erythromicyn, monooxygenase
• 由来する生物種: SACCHAROPOLYSPORA ERYTHRAEA
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48134.86

構造登録者

Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kedrew, S.G.,Gianni, S.,Vallone, B. (登録日: 2009-05-14, 公開日: 2009-07-21, 最終更新日: 2023-12-13)

• 主引用文献: Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Jemth, P.,Gianni, S.,Vallone, B.; Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.; J.Biol.Chem., 284:29170-, 2009; PubMed: 19625248; DOI: 10.1074/JBC.M109.003590

実験手法

X-RAY DIFFRACTION (2 Å)