2WI9
Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase
Summary for 2WI9
Entry DOI | 10.2210/pdb2wi9/pdb |
Related | 2BVJ 2C6H 2C7X 2CA0 2CD8 2VZ7 2VZM 2WHW |
Descriptor | CYTOCHROME P450 HYDROXYLASE PIKC, PROTOPORPHYRIN IX CONTAINING FE, CYCLODODECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE, ... (5 entities in total) |
Functional Keywords | antibiotic biosynthesis, cyp107l1, cytochrome p450, heme, iron, macrolide monooxygenase, metal-binding, monooxygenase, oxidoreductase, oxidoreductase antibiotic biosynthesis, pikc |
Biological source | STREPTOMYCES VENEZUELAE |
Total number of polymer chains | 2 |
Total formula weight | 98567.50 |
Authors | Li, S.,Chaulagain, M.R.,Knauff, A.R.,Podust, L.M.,Montgomery, J.,Sherman, D.H. (deposition date: 2009-05-08, release date: 2009-10-27, Last modification date: 2023-12-13) |
Primary citation | Li, S.,Chaulagain, M.R.,Knauff, A.R.,Podust, L.M.,Montgomery, J.,Sherman, D.H. Selective Oxidation of Carbolide C-H Bonds by an Engineered Macrolide P450 Mono-Oxygenase. Proc.Natl.Acad.Sci.USA, 106:18463-, 2009 Cited by PubMed: 19833867DOI: 10.1073/PNAS.0907203106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report