2WI9

Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CYTOCHROME P450 HYDROXYLASE PIKC	polymer	436	48181.6	2	UniProt (O87605) Pfam (PF00067)	STREPTOMYCES VENEZUELAE	PIKC
2	C, E (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	D, F (A, B)	CYCLODODECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE	non-polymer		341.5	2	Chemie (1D2)
4	G, H, I (B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	J, K (A, B)	water	water		18.0	576	Chemie (HOH)

Sequence modifications

A, B: -19 - 0 (PDB: 2WI9)
A, B: 1 - 416 (UniProt: O87605)

PDB	External Database	Details
Asn 50	Asp 50	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96363.3
Non-Polymers*	Number of molecules	7
	Total formula weight	2204.2
All*	Total formula weight	98567.5

*Water molecules are not included.