2WI9
Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CYTOCHROME P450 HYDROXYLASE PIKC | polymer | 436 | 48181.6 | 2 | UniProt (O87605) Pfam (PF00067) In PDB | STREPTOMYCES VENEZUELAE | PIKC |
| 2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | A, B | CYCLODODECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE | non-polymer | 341.5 | 2 | Chemie (1D2) | |||
| 4 | B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 576 | Chemie (HOH) |
Sequence modifications
A, B: -19 - 0 (PDB: 2WI9)
A, B: 1 - 416 (UniProt: O87605)
A, B: 1 - 416 (UniProt: O87605)
| PDB | External Database | Details |
|---|---|---|
| Asn 50 | Asp 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 96363.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2204.2 | |
| All* | Total formula weight | 98567.5 |
