2WI9

Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase

2WI9 の概要

• エントリーDOI: 10.2210/pdb2wi9/pdb
• 関連するPDBエントリー: 2BVJ 2C6H 2C7X 2CA0 2CD8 2VZ7 2VZM 2WHW
• 分子名称: CYTOCHROME P450 HYDROXYLASE PIKC, PROTOPORPHYRIN IX CONTAINING FE, CYCLODODECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE, ... (5 entities in total)
• 機能のキーワード: antibiotic biosynthesis, cyp107l1, cytochrome p450, heme, iron, macrolide monooxygenase, metal-binding, monooxygenase, oxidoreductase, oxidoreductase antibiotic biosynthesis, pikc
• 由来する生物種: STREPTOMYCES VENEZUELAE
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98567.50

構造登録者

Li, S.,Chaulagain, M.R.,Knauff, A.R.,Podust, L.M.,Montgomery, J.,Sherman, D.H. (登録日: 2009-05-08, 公開日: 2009-10-27, 最終更新日: 2023-12-13)

• 主引用文献: Li, S.,Chaulagain, M.R.,Knauff, A.R.,Podust, L.M.,Montgomery, J.,Sherman, D.H.; Selective Oxidation of Carbolide C-H Bonds by an Engineered Macrolide P450 Mono-Oxygenase.; Proc.Natl.Acad.Sci.USA, 106:18463-, 2009; PubMed: 19833867; DOI: 10.1073/PNAS.0907203106

実験手法

X-RAY DIFFRACTION (2 Å)