2WH6
Crystal structure of anti-apoptotic BHRF1 in complex with the Bim BH3 domain
Summary for 2WH6
Entry DOI | 10.2210/pdb2wh6/pdb |
Related | 1Q59 2V6Q 2VM6 |
Descriptor | EARLY ANTIGEN PROTEIN R, BCL-2-LIKE PROTEIN 11, BROMIDE ION, ... (5 entities in total) |
Functional Keywords | mitochondrion, early protein, transmembrane, viral protein, apoptosis |
Biological source | Epstein-barr virus strain ag876 More |
Cellular location | Host membrane ; Single-pass membrane protein : P03182 Endomembrane system ; Peripheral membrane protein . Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion: O43521 |
Total number of polymer chains | 2 |
Total formula weight | 24026.38 |
Authors | Kvansakul, M.,Huang, D.C.S.,Colman, P.M. (deposition date: 2009-05-01, release date: 2010-05-26, Last modification date: 2023-12-13) |
Primary citation | Kvansakul, M.,Wei, A.H.,Fletcher, J.I.,Willis, S.N.,Chen, L.,Roberts, A.W.,Huang, D.C.,Colman, P.M. Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1. PLoS Pathog., 6:e1001236-e1001236, 2010 Cited by PubMed: 21203485DOI: 10.1371/journal.ppat.1001236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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