2WGT

Structure of human adenovirus serotype 37 fibre head in complex with a sialic acid derivative, O-Methyl 5-N-propaonyl-3,5-dideoxy-D- glycero-a-D-galacto-2-nonulopyranosylonic acid

2WGT の概要

• エントリーDOI: 10.2210/pdb2wgt/pdb
• 関連するPDBエントリー: 1UXA 1UXB 1UXE 2J12 2WGU
• 分子名称: FIBER PROTEIN, 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ZINC ION, ... (4 entities in total)
• 機能のキーワード: sialic acid, viral protein, conjunctivitis, daf, ad37, cd46, receptor, neuraminic acid
• 由来する生物種: HUMAN ADENOVIRUS 37
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 66315.72

構造登録者

Johansson, S.,Nilsson, E.,Qian, W.,Guilligay, D.,Crepin, T.,Cusack, S.,Arnberg, N.,Elofsson, M. (登録日: 2009-04-27, 公開日: 2009-11-24, 最終更新日: 2023-12-13)

• 主引用文献: Johansson, S.,Nilsson, E.,Qian, W.,Guilligay, D.,Crepin, T.,Cusack, S.,Arnberg, N.,Elofsson, M.; Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis.; J.Med.Chem., 52:3666-, 2009; PubMed: 19456100; DOI: 10.1021/JM801609S

実験手法

X-RAY DIFFRACTION (1.8 Å)