2WGI
Crystal structure of the acyl-enzyme OXA-10 W154A-benzylpenicillin at pH 6
Summary for 2WGI
Entry DOI | 10.2210/pdb2wgi/pdb |
Related | 1E3U 1E4D 1EWZ 1FOF 1K4E 1K4F 1K54 1K55 1K56 1K57 1K6R 1K6S |
Descriptor | BETA-LACTAMASE OXA-10, OPEN FORM - PENICILLIN G, GLYCEROL, ... (4 entities in total) |
Functional Keywords | hydrolase-antibiotic complex, hydrolase antibiotic complex, lysine carboxylation, hydrolase, acyl-enzyme, antibiotic resistance, class d beta-lactamase, hydrolase/antibiotic |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 2 |
Total formula weight | 55959.72 |
Authors | Vercheval, L.,Falzone, C.,Sauvage, E.,Herman, R.,Charlier, P.,Galleni, M.,Kerff, F. (deposition date: 2009-04-20, release date: 2009-11-10, Last modification date: 2023-12-13) |
Primary citation | Baurin, S.,Vercheval, L.,Bouillenne, F.,Falzone, C.,Brans, A.,Jacquamet, L.,Ferrer, J.L.,Sauvage, E.,Dehareng, D.,Frere, J.M.,Charlier, P.,Galleni, M.,Kerff, F. Critical Role of Tryptophan 154 for the Activity and Stability of Class D Beta-Lactamases. Biochemistry, 48:11252-, 2009 Cited by PubMed: 19860471DOI: 10.1021/BI901548C PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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