2WFT
Crystal structure of the human HIP ectodomain
Summary for 2WFT
Entry DOI | 10.2210/pdb2wft/pdb |
Related | 2WFQ 2WFR 2WFX 2WG3 2WG4 |
Descriptor | HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | membrane, secreted, cytoplasm, development, disulfide bond, egf-like domain, hedgehog signalling, signal transduction, alternative splicing, polymorphism, glycoprotein, cell membrane, signaling protein |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cell membrane; Peripheral membrane protein (By similarity). Isoform 2: Cytoplasm (Probable): Q96QV1 |
Total number of polymer chains | 2 |
Total formula weight | 102433.41 |
Authors | Bishop, B.,Aricescu, A.R.,Harlos, K.,O'Callaghan, C.A.,Jones, E.Y.,Siebold, C. (deposition date: 2009-04-15, release date: 2009-06-30, Last modification date: 2011-07-13) |
Primary citation | Bishop, B.,Aricescu, A.R.,Harlos, K.,O'Callaghan, C.A.,Jones, E.Y.,Siebold, C. Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16:698-, 2009 Cited by PubMed: 19561611DOI: 10.1038/NSMB.1607 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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