Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| B | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA B 1671 |
| Chain | Residue |
| B | HIS234 |
| B | SER235 |
| B | ASP237 |
| B | SER239 |
| B | GLN240 |
| B | ARG241 |
| B | GLU558 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 1672 |
| Chain | Residue |
| A | SER239 |
| A | GLN240 |
| A | ARG241 |
| A | GLU558 |
| A | SER235 |
| A | ASP237 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 1673 |
| Chain | Residue |
| A | HIS440 |
| A | ASP443 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1674 |
| Chain | Residue |
| A | HIS440 |
| A | PRO441 |
| A | THR442 |
| A | ASP443 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1672 |
| Chain | Residue |
| B | ARG434 |
| B | VAL437 |
| B | VAL496 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1673 |
| Chain | Residue |
| B | GLY631 |
| B | ASP632 |
| B | PHE633 |
| B | ARG635 |
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CcCspGweGDfC |
| Chain | Residue | Details |
| A | CYS623-CYS634 | |
| A | CYS655-CYS666 | |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. CcCspGWegdf....C |
| Chain | Residue | Details |
| A | CYS623-CYS634 | |
| A | CYS655-CYS666 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 54 |
| Details | Domain: {"description":"EGF-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 64 |
| Details | Domain: {"description":"EGF-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Region: {"description":"Interaction with SHH zinc binding site"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19561611","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1c9u |
| Chain | Residue | Details |
| A | HIS352 | |
| A | ASP371 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1c9u |
| Chain | Residue | Details |
| B | HIS352 | |
| B | ASP371 | |
