2WEK

Crystal structure of the human MGC45594 gene product in complex with diclofenac

Summary for 2WEK

• Entry DOI: 10.2210/pdb2wek/pdb
• Related: 2C0C
• Descriptor: ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ... (7 entities in total)
• Functional Keywords: nadp, oxidoreductase, drug metabolism, medium-chain dehydrogenase/reductase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Peroxisome (By similarity): Q8N4Q0
• Total number of polymer chains: 2
• Total formula weight: 77114.23

Authors

Shafqat, N.,Yue, W.W.,Ugochukwu, E.,Niesen, F.,Smee, C.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2009-03-31, release date: 2009-12-15, Last modification date: 2023-12-13)

• Primary citation: Shafqat, N.,Yue, W.W.,Niesen, F.,Oppermann, U.; Crystal Structure of the Human Mgc45594 Gene Product in Complex with Diclofenac; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)