2WEI

Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1

2WEI の概要

• エントリーDOI: 10.2210/pdb2wei/pdb
• 分子名称: CALMODULIN-DOMAIN PROTEIN KINASE 1, PUTATIVE, 1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total)
• 機能のキーワード: nucleotide-binding, serine/threonine-protein kinase, kinase, transferase, atp-binding
• 由来する生物種: CRYPTOSPORIDIUM PARVUM IOWA II
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33740.78

構造登録者

Roos, A.K.,King, O.,Chaikuad, A.,Zhang, C.,Shokat, K.M.,Wernimont, A.K.,Artz, J.D.,Lin, L.,MacKenzie, F.I.,Finerty, P.J.,Vedadi, M.,Schapira, M.,Indarte, M.,Kozieradzki, I.,Pike, A.C.W.,Fedorov, O.,Doyle, D.,Muniz, J.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,von Delft, F.,Heightman, T.,Hui, R. (登録日: 2009-03-31, 公開日: 2009-04-28, 最終更新日: 2023-12-13)

• 主引用文献: Artz, J.D.,Wernimont, A.K.,Allali-Hassani, A.,Zhao, Y.,Amani, M.,Lin, Y.H.,Senisterra, G.,Wasney, G.A.,Fedorov, O.,King, O.,Roos, A.K.,Lunin, V.V.,Qiu, W.,Finerty, P.J.,Hutchinson, A.,Chau, I.,von Delft, F.,MacKenzie, F.I.,Lew, J.,Kozieradzki, I.,Vedadi, M.,Schapira, M.,Zhang, C.,Shokat, K.M.,Heightman, T.,Hui, R.; The Cryptosporidium Parvum Kinome.; Bmc Genomics, 12:478-, 2011; PubMed: 21962082; DOI: 10.1186/1471-2164-12-478

実験手法

X-RAY DIFFRACTION (1.65 Å)