2WD9
CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN
Summary for 2WD9
Entry DOI | 10.2210/pdb2wd9/pdb |
Related | 2VZE |
Descriptor | ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, IBUPROFEN, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | nucleotide-binding, fatty acid metabolism, transit peptide, lipid metabolism, nucleotide binding, mitochondrion, metal-binding, ligase activity, medium-chain fatty acid, fatty acid metabolic process, ligase, magnesium, atp-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 3 |
Total formula weight | 190286.77 |
Authors | Yue, W.W.,Kochan, G.T.,Pilka, E.S.,Bhatia, C.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Oppermann, U. (deposition date: 2009-03-21, release date: 2009-04-21, Last modification date: 2023-12-13) |
Primary citation | Kochan, G.,Pilka, E.S.,Delft, F.V.,Oppermann, U.,Yue, W.W. Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A. J.Mol.Biol., 388:997-, 2009 Cited by PubMed: 19345228DOI: 10.1016/J.JMB.2009.03.064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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