2WB3

The partial structure of a group A streptococcal phage-encoded tail fibre hyaluronate lyase Hylp3

Summary for 2WB3

Entry DOI	10.2210/pdb2wb3/pdb
Descriptor	HYALURONIDASE-PHAGE ASSOCIATED (2 entities in total)
Functional Keywords	lyase, hyaluronan lyase, phage tail fibre, triple-stranded beta- helix, hyaluronidase, scarlet fever
Biological source	STREPTOCOCCUS PYOGENES
Total number of polymer chains	1
Total formula weight	16854.13
Authors	Martinez-Fleites, C.,Black, G.W.,Turkenburg, J.P.,Smith, N.L.,Taylor, E.J. (deposition date: 2009-02-20, release date: 2009-09-01, Last modification date: 2024-05-08)
Primary citation	Martinez-Fleites, C.,Smith, N.L.,Turkenburg, J.P.,Black, G.W.,Taylor, E.J. Structures of Two Truncated Phage-Tail Hyaluronate Lyases from Streptococcus Pyogenes Serotype M1. Acta Crystallogr.,Sect.F, 65:963-, 2009 Cited by PubMed Abstract: The crystal structures of truncated forms of the Streptococcus pyogenes phage-encoded hyaluronate lyases HylP2 and HylP3 were determined by molecular replacement to 1.6 and 1.9 A resolution, respectively. The truncated forms crystallized in a hexagonal space group, forming a trimer around the threefold crystallographic axis. The arrangement of the fold is very similar to that observed in the structure of the related hyaluronate lyase HylP1. The structural elements putatively involved in substrate recognition are found to be conserved in both the HylP2 and HylP3 fragments. PubMed: 19850999 DOI: 10.1107/S1744309109032813 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation