2WAE
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Summary for 2WAE
Entry DOI | 10.2210/pdb2wae/pdb |
Related | 2WAD 2WAF |
Descriptor | PENICILLIN-BINDING PROTEIN 2B, ZINC ION (3 entities in total) |
Functional Keywords | peptidoglycan synthesis, penicillin-binding protein, transmembrane, antibiotic resistance, cell shape, peptidoglycan, cell membrane, cell wall biogenesis/degradation, membrane, infection, resistance, antibiotic, peptide binding protein |
Biological source | STREPTOCOCCUS PNEUMONIAE |
Cellular location | Cell membrane; Single-pass membrane protein (By similarity): P0A3M6 |
Total number of polymer chains | 1 |
Total formula weight | 73893.92 |
Authors | Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. (deposition date: 2009-02-05, release date: 2009-02-24, Last modification date: 2023-12-13) |
Primary citation | Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci J.Mol.Biol., 387:899-, 2009 Cited by PubMed: 19233207DOI: 10.1016/J.JMB.2009.02.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
Download full validation report