2WAD

PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)

2WAD の概要

• エントリーDOI: 10.2210/pdb2wad/pdb
• 関連するPDBエントリー: 2WAE 2WAF
• 分子名称: PENICILLIN-BINDING PROTEIN 2B, ZINC ION (3 entities in total)
• 機能のキーワード: peptidoglycan synthesis, penicillin-binding protein, transmembrane, antibiotic resistance, cell shape, peptidoglycan, cell membrane, cell wall biogenesis/degradation, membrane, infection, resistance, antibiotic, peptide binding protein
• 由来する生物種: STREPTOCOCCUS PNEUMONIAE
• 細胞内の位置: Cell membrane; Single-pass membrane protein (By similarity): P0A3M6
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 222035.21

構造登録者

Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. (登録日: 2009-02-05, 公開日: 2009-02-24, 最終更新日: 2014-02-19)

• 主引用文献: Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A.; Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci; J.Mol.Biol., 387:899-, 2009; PubMed: 19233207; DOI: 10.1016/J.JMB.2009.02.024

実験手法

X-RAY DIFFRACTION (2.18 Å)