2W9H
Wild-type Staphylococcus aureus DHFR in complex with trimethoprim
Summary for 2W9H
Entry DOI | 10.2210/pdb2w9h/pdb |
Related | 2W9G |
Descriptor | DIHYDROFOLATE REDUCTASE, 1,2-ETHANEDIOL, TRIMETHOPRIM, ... (4 entities in total) |
Functional Keywords | oxidoreductase, one-carbon metabolism |
Biological source | STAPHYLOCOCCUS AUREUS |
Total number of polymer chains | 1 |
Total formula weight | 18628.32 |
Authors | Soutter, H.H.,Miller, J.R. (deposition date: 2009-01-23, release date: 2009-03-24, Last modification date: 2011-07-13) |
Primary citation | Heaslet, H.,Harris, M.,Fahnoe, K.,Sarver, R.,Putz, H.,Chang, J.,Subramanian, C.,Barreiro, G.,Miller, J.R. Structural Comparison of Chromosomal and Exogenous Dihydrofolate Reductase from Staphylococcus Aureus in Complex with the Potent Inhibitor Trimethoprim. Proteins, 76:706-, 2009 Cited by PubMed: 19280600DOI: 10.1002/PROT.22383 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
Download full validation report