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2W9H

Wild-type Staphylococcus aureus DHFR in complex with trimethoprim

Summary for 2W9H
Entry DOI10.2210/pdb2w9h/pdb
Related2W9G
DescriptorDIHYDROFOLATE REDUCTASE, 1,2-ETHANEDIOL, TRIMETHOPRIM, ... (4 entities in total)
Functional Keywordsoxidoreductase, one-carbon metabolism
Biological sourceSTAPHYLOCOCCUS AUREUS
Total number of polymer chains1
Total formula weight18628.32
Authors
Soutter, H.H.,Miller, J.R. (deposition date: 2009-01-23, release date: 2009-03-24, Last modification date: 2011-07-13)
Primary citationHeaslet, H.,Harris, M.,Fahnoe, K.,Sarver, R.,Putz, H.,Chang, J.,Subramanian, C.,Barreiro, G.,Miller, J.R.
Structural Comparison of Chromosomal and Exogenous Dihydrofolate Reductase from Staphylococcus Aureus in Complex with the Potent Inhibitor Trimethoprim.
Proteins, 76:706-, 2009
Cited by
PubMed: 19280600
DOI: 10.1002/PROT.22383
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.48 Å)
Structure validation

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