2W86

Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form

Summary for 2W86

Entry DOI	10.2210/pdb2w86/pdb
Related	1APJ 1LMJ 1UZJ 1UZK 1UZP 1UZQ
Descriptor	FIBRILLIN-1, CALCIUM ION, IODIDE ION, ... (4 entities in total)
Functional Keywords	fibrillin, phosphoprotein, egf-like domain, disease mutation, craniosynostosis, extracellular matrix, fibrillin calcium cbegf hybrid, calcium, secreted, polymorphism, glycoprotein
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted, extracellular space, extracellular matrix: P35555
Total number of polymer chains	1
Total formula weight	15988.58
Authors	Jensen, S.A.,Iqbal, S.,Lowe, E.D.,Redfield, C.,Handford, P.A. (deposition date: 2009-01-09, release date: 2009-05-26, Last modification date: 2011-07-13)
Primary citation	Jensen, S.A.,Iqbal, S.,Lowe, E.D.,Redfield, C.,Handford, P.A. Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins. Structure, 17:759-, 2009 Cited by PubMed: 19446531 DOI: 10.1016/J.STR.2009.03.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation