2W5A

Human Nek2 kinase ADP-bound

2W5A の概要

• エントリーDOI: 10.2210/pdb2w5a/pdb
• 関連するPDBエントリー: 2JAV 2W5B 2W5H
• 分子名称: SERINE/THREONINE-PROTEIN KINASE NEK2, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: ser/thr protein kinase, kinase, nucleus, meiosis, mitosis, cytoplasm, serine/threonine-protein kinase, metal-binding, phosphoprotein, nucleotide-binding, magnesium, cell cycle, atp-binding, transferase, centrosome splitting, alternative splicing, coiled coil, polymorphism, cell division
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33362.26

構造登録者

Westwood, I.,Bayliss, R. (登録日: 2008-12-08, 公開日: 2008-12-23, 最終更新日: 2024-05-08)

• 主引用文献: Westwood, I.,Cheary, D.M.,Baxter, J.E.,Richards, M.W.,Van Montfort, R.L.,Fry, A.M.,Bayliss, R.; Insights Into the Conformational Variability and Regulation of Human Nek2 Kinase.; J.Mol.Biol., 386:476-, 2009; PubMed: 19124027; DOI: 10.1016/J.JMB.2008.12.033

実験手法

X-RAY DIFFRACTION (1.55 Å)