2W4R

Crystal structure of the regulatory domain of human LGP2

Summary for 2W4R

• Entry DOI: 10.2210/pdb2w4r/pdb
• Descriptor: PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, MERCURY (II) ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: innate immunity, immune response, nucleotide-binding, coiled coil, atp-binding, polymorphism, double-strand rna binding protein, helicase, hydrolase, cytoplasm, rna-binding
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: Q96C10
• Total number of polymer chains: 4
• Total formula weight: 66137.29

Authors

Pippig, D.A.,Hellmuth, J.C.,Cui, S.,Kirchhofer, A.,Lammens, K.,Lammens, A.,Schmidt, A.,Rothenfusser, S.,Hopfner, K.P. (deposition date: 2008-12-01, release date: 2009-02-24, Last modification date: 2023-12-13)

• Primary citation: Pippig, D.A.,Hellmuth, J.C.,Cui, S.,Kirchhofer, A.,Lammens, K.,Lammens, A.,Schmidt, A.,Rothenfusser, S.,Hopfner, K.P.; The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.; Nucleic Acids Res., 37:2014-, 2009; PubMed: 19208642; DOI: 10.1093/NAR/GKP059

Experimental method

X-RAY DIFFRACTION (2.6 Å)