2W2G

Human SARS coronavirus unique domain

2W2G の概要

• エントリーDOI: 10.2210/pdb2w2g/pdb
• 関連するPDBエントリー: 1Q2W 1QZ8 2FE8 2WCT
• 分子名称: NON-STRUCTURAL PROTEIN 3, SULFATE ION (3 entities in total)
• 機能のキーワード: thiol protease, rna replication, viral replicase, rna-binding, zinc-finger, ribosomal frameshifting, hydrolase, rna-binding protein, rna binding protein
• 由来する生物種: SARS CORONAVIRUS
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58653.76

構造登録者

Tan, J.,Vonrhein, C.,Smart, O.S.,Bricogne, G.,Bollati, M.,Kusov, Y.,Hansen, G.,Mesters, J.R.,Schmidt, C.L.,Hilgenfeld, R. (登録日: 2008-10-30, 公開日: 2009-05-26, 最終更新日: 2023-12-13)

• 主引用文献: Tan, J.,Vonrhein, C.,Smart, O.S.,Bricogne, G.,Bollati, M.,Kusov, Y.,Hansen, G.,Mesters, J.R.,Schmidt, C.L.,Hilgenfeld, R.; The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.; Plos Pathog., 5:428-, 2009; PubMed: 19436709; DOI: 10.1371/JOURNAL.PPAT.1000428

実験手法

X-RAY DIFFRACTION (2.22 Å)