2W19

Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis

2W19 の概要

• エントリーDOI: 10.2210/pdb2w19/pdb
• 関連するPDBエントリー: 2B7O 2VKL 2W1A
• 分子名称: 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, CHORISMATE MUTASE, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: transferase-isomerase complex, transferase isomerase complex, aromatic amino acid biosynthesis, multi-enzyme complex, protein-protein interactions, enzyme activation, feedback regulation, shikimate pathway, complex formation, mycobacterium tuberculosis rv0948c, isomerase, transferase, drug target, enzyme catalysis, transferase/isomerase
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 125299.94

構造登録者

Okvist, M.,Sasso, S.,Roderer, K.,Gamper, M.,Codoni, G.,Krengel, U.,Kast, P. (登録日: 2008-10-16, 公開日: 2009-07-07, 最終更新日: 2023-12-13)

• 主引用文献: Sasso, S.,Okvist, M.,Roderer, K.,Gamper, M.,Codoni, G.,Krengel, U.,Kast, P.; Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner.; Embo J., 28:2128-, 2009; PubMed: 19556970; DOI: 10.1038/EMBOJ.2009.165

実験手法

X-RAY DIFFRACTION (2.15 Å)