2W0B
CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR 3-{[(4-METHYLPHENYL)SULFONYL]AMINO}PROPYL PYRIDIN-4-YLCARBAMATE
Summary for 2W0B
Entry DOI | 10.2210/pdb2w0b/pdb |
Related | 1E9X 1EA1 1H5Z 1U13 1X8V 2BZ9 2CI0 2CIB 2VKU 2W09 2W0A |
Descriptor | CYTOCHROME P450 51, PROTOPORPHYRIN IX CONTAINING FE, 3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate, ... (4 entities in total) |
Functional Keywords | steroid biosynthesis, protein-inhibitor complex, metal-binding, oxidoreductase, lipid synthesis, nadp, iron, heme, cytoplasm, monooxygenase, sterol biosynthesis |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 1 |
Total formula weight | 52443.18 |
Authors | Podust, L.M. (deposition date: 2008-08-12, release date: 2009-01-20, Last modification date: 2023-12-13) |
Primary citation | Chen, C.K.,Doyle, P.S.,Yermalitskaya, L.V.,Mackey, Z.B.,Ang, K.K.,McKerrow, J.H.,Podust, L.M. Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit. Plos Negl Trop Dis, 3:e372-e372, 2009 Cited by PubMed: 19190730DOI: 10.1371/journal.pntd.0000372 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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