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2W0B

CYP51 OF M. TUBERCULOSIS BOUND TO AN INHIBITOR 3-{[(4-METHYLPHENYL)SULFONYL]AMINO}PROPYL PYRIDIN-4-YLCARBAMATE

Summary for 2W0B
Entry DOI10.2210/pdb2w0b/pdb
Related1E9X 1EA1 1H5Z 1U13 1X8V 2BZ9 2CI0 2CIB 2VKU 2W09 2W0A
DescriptorCYTOCHROME P450 51, PROTOPORPHYRIN IX CONTAINING FE, 3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate, ... (4 entities in total)
Functional Keywordssteroid biosynthesis, protein-inhibitor complex, metal-binding, oxidoreductase, lipid synthesis, nadp, iron, heme, cytoplasm, monooxygenase, sterol biosynthesis
Biological sourceMYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains1
Total formula weight52443.18
Authors
Podust, L.M. (deposition date: 2008-08-12, release date: 2009-01-20, Last modification date: 2023-12-13)
Primary citationChen, C.K.,Doyle, P.S.,Yermalitskaya, L.V.,Mackey, Z.B.,Ang, K.K.,McKerrow, J.H.,Podust, L.M.
Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.
Plos Negl Trop Dis, 3:e372-e372, 2009
Cited by
PubMed: 19190730
DOI: 10.1371/journal.pntd.0000372
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.56 Å)
Structure validation

217705

数据于2024-03-27公开中

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