2VZM

Crystal structure of the narbomycin-bound PikC D50N mutant

Summary for 2VZM

Entry DOI	10.2210/pdb2vzm/pdb
Related	2BVJ 2C6H 2C7X 2CA0 2CD8 2VSJ 2VZ7
Descriptor	CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, NARBOMYCIN, ... (4 entities in total)
Functional Keywords	oxidoreductase, pikc, iron, heme, cyp107l1, monooxygenase, antibiotic biosynthesis, macrolide monooxygenase, metal-binding, cytochrome p450
Biological source	STREPTOMYCES VENEZUELAE
Total number of polymer chains	2
Total formula weight	98787.84
Authors	Li, S.,Sherman, D.H.,Podust, L.M. (deposition date: 2008-08-01, release date: 2008-08-12, Last modification date: 2023-12-13)
Primary citation	Li, S.,Ouellet, H.,Sherman, D.H.,Podust, L.M. Analysis of Transient and Catalytic Desosamine Binding Pockets in Cytochrome P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 284:5723-, 2009 Cited by PubMed: 19124459 DOI: 10.1074/JBC.M807592200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation