2VZM

Crystal structure of the narbomycin-bound PikC D50N mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CYTOCHROME P450 MONOOXYGENASE	polymer	436	48267.8	2	UniProt (O87605)	STREPTOMYCES VENEZUELAE	PIKC, CYTOCHROME P450 HYDROXYLASE PIKC
2	C, E (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	D, F (A, B)	NARBOMYCIN	non-polymer		509.7	2	Chemie (NRB) PubChem (24871490) PubChem (177397199) PubChem (101790022) PubChem (5485603) PubChem (9957969) PubChem (163034475) PubChem (173794856) PubChem (74340065) PubChem (5282036) PubChem (6437585) PubChem (10062745) PubChem (141646831) PubChem (163034473) PubChem (163034474) PubChem (145400974)
4	G, H (A, B)	water	water		18.0	641	Chemie (HOH)

Sequence modifications

A, B: -19 - 0 (PDB: 2VZM)
A, B: 1 - 416 (UniProt: O87605)

PDB	External Database	Details
Asn 50	Asp 50	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96535.5
Non-Polymers*	Number of molecules	4
	Total formula weight	2252.3
All*	Total formula weight	98787.8

*Water molecules are not included.