2VZM

Crystal structure of the narbomycin-bound PikC D50N mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CYTOCHROME P450 MONOOXYGENASE	polymer	436	48267.8	2	UniProt (O87605) Pfam (PF00067)	STREPTOMYCES VENEZUELAE	PIKC, CYTOCHROME P450 HYDROXYLASE PIKC
2	C, E (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	D, F (A, B)	NARBOMYCIN	non-polymer		509.7	2	Chemie (NRB)
4	G, H (A, B)	water	water		18.0	641	Chemie (HOH)

Sequence modifications

A, B: -19 - 0 (PDB: 2VZM)
A, B: 1 - 416 (UniProt: O87605)

PDB	External Database	Details
Asn 50	Asp 50	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96535.5
Non-Polymers*	Number of molecules	4
	Total formula weight	2252.3
All*	Total formula weight	98787.8

*Water molecules are not included.