2VVW

Structure of Vaccinia virus protein A52

Summary for 2VVW

Entry DOI	10.2210/pdb2vvw/pdb
Related	2I39 2JBX 2JBY 2UXE 2VVX 2VVY
Descriptor	PROTEIN A52 (2 entities in total)
Functional Keywords	irak2, traf6, bcl-2 family, vaccinia virus, immunomodulator, nf-kb activation, viral protein, host-virus interaction
Biological source	VACCINIA VIRUS
Total number of polymer chains	2
Total formula weight	39179.41
Authors	Graham, S.C.,Bahar, M.W.,Cooray, S.,Chen, R.A.-J.,Whalen, D.M.,Abrescia, N.G.A.,Alderton, D.,Owens, R.J.,Stuart, D.I.,Smith, G.L.,Grimes, J.M. (deposition date: 2008-06-12, release date: 2008-08-26, Last modification date: 2019-05-08)
Primary citation	Graham, S.C.,Bahar, M.W.,Cooray, S.,Chen, R.A.-J.,Whalen, D.M.,Abrescia, N.G.A.,Alderton, D.,Owens, R.J.,Stuart, D.I.,Smith, G.L.,Grimes, J.M. Vaccinia Virus Proteins A52 and B14 Share a Bcl-2-Like Fold But Have Evolved to Inhibit NF-kappaB Rather Than Apoptosis Plos Pathog., 4:E128-, 2008 Cited by PubMed: 18704168 DOI: 10.1371/JOURNAL.PPAT.1000128 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation