2VTX

ACTIVATION OF NUCLEOPLASMIN, AN OLIGOMERIC HISTONE CHAPERONE, CHALLENGES ITS STABILITY

Summary for 2VTX

DescriptorNPM-A PROTEIN (3 entities in total)
Functional Keywordsnucleoplasmin, phosphorylation, protein stability, oligomeric protein, nuclear protein
Biological sourceXENOPUS LAEVIS (AFRICAN CLAWED FROG)
Total number of polymer chains10
Total molecular weight133853.73
Authors
Taneva, S.G.,Munoz, I.G.,Franco, G.,Falces, J.,Arregi, I.,Muga, A.,Montoya, G.,Urbaneja, M.A.,Banuelos, S. (deposition date: 2008-05-16, release date: 2008-12-16, Last modification date: 2011-07-13)
Primary citation
Taneva, S.G.,Munoz, I.G.,Franco, G.,Falces, J.,Arregi, I.,Muga, A.,Montoya, G.,Urbaneja, M.A.,Banuelos, S.
Activation of Nucleoplasmin, an Oligomeric Histone Chaperone, Challenges its Stability.
Biochemistry, 47:13897-, 2008
PubMed: 19055325 (PDB entries with the same primary citation)
DOI: 10.1021/BI800975R
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27191.0%10.4%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution