2VN9
Crystal Structure of Human Calcium Calmodulin dependent Protein Kinase II delta isoform 1, CAMKD
Summary for 2VN9
| Entry DOI | 10.2210/pdb2vn9/pdb |
| Descriptor | CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA CHAIN, PHOSPHATE ION, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | serine/threonine-protein kinase, serine-threonine kinase, cellular differentiation, vascular smooth muscle, kinase, transferase, atp-binding, phosphoprotein, calmodulin-binding, nucleotide-binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side : Q13557 |
| Total number of polymer chains | 2 |
| Total formula weight | 69923.42 |
| Authors | Roos, A.K.,Rellos, P.,Salah, E.,Pike, A.C.W.,Fedorov, O.,Pilka, E.S.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Knapp, S. (deposition date: 2008-01-31, release date: 2008-02-26, Last modification date: 2023-12-13) |
| Primary citation | Rellos, P.,Pike, A.C.W.,Niesen, F.H.,Salah, E.,Lee, W.H.,von Delft, F.,Knapp, S. Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation. Plos Biol., 8:426-, 2010 Cited by PubMed: 20668654DOI: 10.1371/JOURNAL.PBIO.1000426 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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