2VN9

Crystal Structure of Human Calcium Calmodulin dependent Protein Kinase II delta isoform 1, CAMKD

2VN9 の概要

• エントリーDOI: 10.2210/pdb2vn9/pdb
• 分子名称: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA CHAIN, PHOSPHATE ION, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: serine/threonine-protein kinase, serine-threonine kinase, cellular differentiation, vascular smooth muscle, kinase, transferase, atp-binding, phosphoprotein, calmodulin-binding, nucleotide-binding
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side : Q13557
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69923.42

構造登録者

Roos, A.K.,Rellos, P.,Salah, E.,Pike, A.C.W.,Fedorov, O.,Pilka, E.S.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Knapp, S. (登録日: 2008-01-31, 公開日: 2008-02-26, 最終更新日: 2023-12-13)

• 主引用文献: Rellos, P.,Pike, A.C.W.,Niesen, F.H.,Salah, E.,Lee, W.H.,von Delft, F.,Knapp, S.; Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.; Plos Biol., 8:426-, 2010; PubMed: 20668654; DOI: 10.1371/JOURNAL.PBIO.1000426

実験手法

X-RAY DIFFRACTION (2.3 Å)