2VJ8

Complex of human leukotriene A4 hydrolase with a hydroxamic acid inhibitor

Summary for 2VJ8

Entry DOI	10.2210/pdb2vj8/pdb
Descriptor	LTA4H PROTEIN, ZINC ION, YTTERBIUM (III) ION, ... (7 entities in total)
Functional Keywords	hydroxamic acid, leukotriene hydrolase, zinc, protease, hydrolase, metalloprotease
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	70477.09
Authors	Thunnissen, M.M.G.M.,Andersson, B.,Wong, C.-H.,Samuelsson, B.,Haeggstrom, J.Z. (deposition date: 2007-12-07, release date: 2008-01-15, Last modification date: 2023-12-13)
Primary citation	Thunnissen, M.M.G.M.,Andersson, B.,Wong, C.-H.,Samuelsson, B.,Haeggstrom, J.Z. Crystal Structures of Leukotriene A4 Hydrolase in Complex with Captopril and Two Competitive Tight-Binding Inhibitors Faseb J., 16:1648-, 2002 Cited by PubMed: 12207002 DOI: 10.1096/FJ.01-1017FJE PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation